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Hashimoto’s thyroiditis

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The immune system attacks the thyroid — a slow process that can be well monitored and balanced when needed.

Also known as: Hashimoto’s thyroiditis · autoimmune thyroiditis · common cause of hypothyroidism

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This compilation is for information and replaces neither medical diagnosis nor treatment. If you have symptoms, see a doctor.

The thyroid sits at the front of the neck and makes two hormones, T4 and T3, which help set the pace of almost every cell. In Hashimoto’s the immune system turns against that tissue over years; in countries with enough iodine it is the commonest cause of an underactive thyroid. Three things are regularly muddled. First the antibodies: TPO antibodies show that an autoimmune process is running — they say nothing about function, they are not treated, and their course does not need repeat measuring. Many people carry them lifelong without ever becoming underactive. Second the TSH: it does not come from the thyroid but from the pituitary, and it rises when too little hormone arrives. A high TSH therefore means a weak thyroid, not an overactive one — that reversal confuses almost everyone at the first report. Third the course: it is rarely a straight line. Early on function can be normal, occasionally even too high for some weeks, before it slowly fades. So it is monitored rather than settled once. The complaints themselves are unspecific and overlap with iron deficiency, anaemia, low mood and the menopause — the value decides, not the feeling.

Levers & pathways

studiedMedical work-up & treatment if needed

Over- or underactivity should be diagnosed and treated (e.g. hormone replacement) — the key step.

studiedEnough iodine – but not too much

Iodine is the building block of thyroid hormones; both deficiency and excess can harm. Iodised salt and sea fish cover the need.

studiedWhen the cold stays although the values are right

Feeling cold does not prove the thyroid. The most common other reasons are an empty iron store and a vitamin B12 deficiency — both produce the same cold and the same tiredness. With autoimmune thyroiditis they come along more often, because the same immune situation can affect the stomach lining, and then less iron and B12 is taken up. Ferritin and B12 show whether something is missing there.

studiedRead TSH and free T4 together

TSH alone only says how loudly the pituitary is calling. Only with free T4 beside it does it become visible whether too little hormone really arrives or only the signal is raised.

studiedAntibodies once, not again and again

TPO antibodies answer the question of cause. They steer no treatment, and their level says nothing about today’s complaints or about what comes next.

studiedAlways measure the same way: morning, before the tablet

TSH swings through the day and is highest in the morning. Measuring once in the morning and once in the afternoon compares two different things and may change a dose because of the clock.

studiedOn tablets: keep distance from calcium, iron and coffee

Calcium and iron supplements bind the hormone in the gut, coffee delays uptake. A steady gap matters more than a perfect one — the main thing is that it is the same every day.

mixedSelenium: what is established and what is not

Studies show selenium can lower antibody levels. Whether complaints or the course change with it is not shown by the studies. A high intake kept up for long is not harmless either.

studiedNo high-dose iodine from algae or cures

Iodised salt and sea fish are a different order of magnitude from algae powder or iodine preparations. Large amounts can trigger or worsen an underactive thyroid in a gland already affected.

studiedWith a wish for children and in pregnancy, look earlier

In pregnancy the targets are tighter and the need often rises within the first weeks. Anyone with antibodies should discuss this before, not after, conception.

associatedKeep an eye on the neighbours

Autoimmune processes cluster: coeliac disease, vitamin B12 deficiency from autoimmune gastritis, vitiligo, type 1 diabetes. That does not mean they will come — only that they belong in mind when new complaints appear.

studiedWhat the medicine does — and what it does not

Levothyroxine replaces the hormone the thyroid no longer makes in sufficient amount. The autoimmune reaction itself is untouched — it carries on, only without consequences for metabolism. That is why the value is checked, not the feeling.

studiedNumbers and timeframes

The most common thyroid condition; women are affected five to ten times more often than men. The underactivity develops over years, often without any single day standing out. After a dose change the value only becomes meaningful again after six to eight weeks.

Possible complaints

studiedTiredness that sleep does not repair

Not a dip after one bad night but a background state over weeks. That is exactly why it proves nothing on its own — iron deficiency and anaemia feel the same.

studiedFeeling cold when others are comfortable

Cold hands and feet, a jumper in summer. The body turns its turnover down when less hormone arrives.

studiedDry skin, brittle hair, thinner eyebrows

Skin and hair renew more slowly. The hair does not go bald in patches but thins overall, and it comes back when function is right again.

studiedA sluggish gut

The whole digestive route slows down. Constipation with no other explanation is therefore a reason to look at the thyroid once.

studiedA few kilos more — not twenty

An underactive thyroid explains a modest gain, usually a few kilos, part of it retained water. A large weight gain almost always has another cause — here the thyroid is more often a suspect than the culprit.

studiedLow mood, slower thinking

Finding words, concentration and drive all fade. That is why thyroid values are measured alongside a new depressive episode.

associatedPressure or tightness in the neck

The gland can swell in the inflammatory phase and shrink later. A rapidly growing, hard or one-sided nodule needs looking at regardless.

Blood values

studiedTPO antibodies

Raised — key autoimmune marker.

studiedTSH

Rises as function declines.

associatedfT4

Falls as hypothyroidism develops.

Nutrients

associatedSelenium

May lower TPO antibodies (moderate evidence).

associatedVitamin D

Low levels are commonly associated.

Supplements

associatedSelenium

Studied as an add-on — don’t overdose.

infoVitamin D3 (+K2)

Clearly worthwhile and well studied when deficient; fewer data for the wider uses. Fat-soluble — check blood levels at high doses.

Hormones

studiedTSH

Master hormone of the thyroid axis.

Food

studiedSelenium — studied, but limited

In studies with 200 µg selenium a day over 3–6 months antibodies fell; whether thyroid function benefits is open. Above 300 µg a day long term counts as too much.

studiedIodine — not on suspicion

Very high iodine amounts can weigh on the course of Hashimoto, and so can deficiency. Normal iodised-salt amounts are not meant; high-dose seaweed preparations are.

mixedGluten-free — the evidence is thin

With coeliac disease alongside, avoidance is needed. Without it small studies give mixed results; anyone trying should hold it for 3 months and then judge by the antibodies.

Alternative approaches — what people use

studiedSelenium

The best-studied supplement in this condition — the antibodies fall in studies, the wellbeing not always.

studiedVitamin D

Low levels are common; measure before supplementing.

studiedDiet change

A gluten-free diet is much recommended; it is established only with coexisting coeliac disease, which is more common here.

TCM — how it is seen there

traditionalPattern diagnosis

TCM does not know autoimmune disease — it describes what the person feels: cold, heaviness, exhaustion. That does not replace the TSH value, it describes alongside it.

infoAristolochic acid & unsafe herbs

The most important entry on this page: some Chinese herbal mixtures contained aristolochic acid — it caused kidney failure and cancer in Europe. Anyone taking Chinese herbs buys where the origin is checked.

Frequencies — what is on file

traditionalHashimoto's

Listed values: 10 · 528 · 741 · 2130 · 8520 Hz