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Vitamin D deficiency

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Common at our latitudes, especially in winter — important for bones and muscles, and easy to clarify with a simple test.

Also known as: vitamin D deficiency · low 25-OH vitamin D

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This compilation is for information and replaces neither medical diagnosis nor treatment. If you have symptoms, see a doctor.

Vitamin D is really a hormone, and the body makes it itself — in the skin, under ultraviolet light. North of the Alps the sun is not enough for this from about October to March: the radiation comes in too flat. So the store empties over the winter, and the lowest values are found in late spring. What is measured is 25-OH vitamin D, because it reflects the store. What counts as a good value is handled differently in different places; there is agreement about the lower limit, below which bones and muscles suffer. The benefit is genuinely established where the shortage is large: in soft bones, in the tendency to fall in older age, in children to prevent rickets. For many further promises the evidence is thinner than the reputation suggests — large studies in people with normal starting levels have shown little. That does not speak against topping up a real deficiency, but against the idea that more is always better. Very high doses over long periods can do harm, because they drive the calcium level. Hence the simple principle: measure first, then dose, and re-check once with longer use.

Levers & pathways

studiedSunlight (UVB on skin)

Skin makes vitamin D from UVB. Works well in summer and at midday — but in Swiss winter the sun is too low.

studiedSupplement vitamin D3 (if deficient)

The most reliable way to raise levels — especially in winter. Dose to your baseline; K2 can sensibly accompany it.

studiedMeasure first, then dose

Very high doses over long periods can harm (calcium). Establish your baseline and match the dose — ideally with a clinician.

studiedNo high doses in the dark

Very high amounts over long periods drive the calcium level and can harm the kidney. More is not better here, and at some point worse.

studiedWith a meal that contains fat

Vitamin D is fat-soluble and taken up much better this way. On an empty stomach part of it is lost.

studiedRe-check after three months

The store fills slowly. A check says whether the chosen amount fits — too little for some, long since enough for others.

studiedIn summer the skin, in winter the capsule

Short spells outdoors with face and arms uncovered are usually enough in summer. In winter that does not work — supplementing is then the simpler route.

studiedWith a very low value, look at calcium too

With a marked shortage the parathyroid hormone rises to hold calcium — at the bone’s expense. The two together show how serious the shortage is.

studiedNumbers and timeframes

Between October and March the sun stands too low at our latitudes for the skin to make vitamin D — no matter how long one stays outside. The level falls over the winter and rises again from April; refilling the store takes eight to twelve weeks.

infoWhat the medicine does — and what it does not

Vitamin D fills a store that builds over weeks: with daily intake the blood level reaches its new plateau in eight to twelve weeks. It acts on bone and calcium — there the benefit is clear when a deficiency is documented. In people with sufficient levels, large trials showed no added benefit for colds, heart or cancer. Too much over months (well above 4000 units a day without checks) drives calcium up.

Possible complaints

studiedUsually no signs at all

A mild shortage is not felt. So the value says more here than the feeling — and without measuring it is easy to take too much or too little.

studiedMuscle weakness, especially standing up

Out of a chair, going upstairs. With a marked shortage, an earlier sign than bone pain.

studiedDull bone pain

Unlike joint pain: deeper, more spread out, often pelvis, ribs or shin, and tender to pressure. A sign of a marked, long shortage.

studiedLittle time outdoors, covered or darker skin

All three lower what the skin can make. Sun protection does too — which does not make it bad, only explains why little forms despite summer.

studiedAfter stomach surgery or with bowel disease

Vitamin D is taken up with fat. Where fat absorption suffers, so does it — the usual dose is then not enough.

studiedSigns on the body

What a deficiency makes visible on the body — skin, nails, tongue, eyes and nerves. The signs are unspecific: they show where to look, they prove nothing.

studiedMuscle pain and weakness

More a dragging in thighs and upper arms than pain in one place, often together with difficulty getting up and climbing stairs.

Blood values

studied25-OH vitamin D

The diagnostic storage value.

associatedPTH

May rise compensatorily.

Nutrients

studiedMagnesium

Cofactor of D activation — often overlooked.

associatedVitamin K2

Discussed synergy in calcium handling.

studiedCalcium

The target vitamin D regulates.

Supplements

studiedVitamin D3

Standard if deficient — dose by level.

studiedMagnesium

Activation cofactor.

associatedVitamin K2

Discussed calcium synergy.

Hormones

studiedParathyroid hormone (PTH)

Counterpart in calcium balance.

Food

associatedOily fish, fortified foods

Diet rarely covers the need — sun/supplement key.

Alternative approaches — what people use

studiedVitamin D

In winter the sun does not reach the necessary angle at our latitudes — which is why the season is decisive here.

studiedVitamin K2

Often supplemented together; the studies on the need for this combination are thin.

studiedMovement & exercise

Being outdoors works twice over — light and movement.

Frequencies — what is on file

traditionalRickets (needs vitamin D and sunlight)

Listed values: 880 · 5000 Hz