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Omega-3 deficiency

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Not too little fat but an unfavourable ratio — fish and plant sources shift it.

Also known as: low omega-3 · fatty-acid imbalance

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This compilation is for information and replaces neither medical diagnosis nor treatment. If you have symptoms, see a doctor.

Omega-3 fatty acids (especially EPA and DHA from oily fish) are building blocks of our cell membranes and act favourably on the heart, brain and inflammation. Many people on a Western diet take in plenty of omega-6 fatty acids (from many plant oils and processed foods) but rather little omega-3 — this imbalance, rather than a dramatic classic “deficiency”, is the real point. A true nutrient deficiency with clear signs of illness is rare, but a better omega-3 supply is regarded as sensible for the long-term health of the heart and vessels. The supply can be measured via the omega-3 index. The simplest and most natural lever is regular oily sea fish; those who don’t eat fish will find plant sources and may consider a supplement.

Levers & pathways

associatedOily sea fish

Regular salmon, herring, mackerel or sardines is the most natural way.

associatedPlant sources

Flax, rapeseed and walnut oil provide the plant precursor (ALA).

associatedDon’t overdo omega-6

Less heavily processed food improves the balance too.

associatedConsider a supplement

Those who dislike fish may consider an omega-3 supplement (with advice).

infoWhat the medicine does — and what it does not

The omega-3 index in the red blood cell needs three to four months to respond to a new intake — the cells live about 120 days. So a measurement after four weeks says nothing. To lower triglycerides, 2 to 4 grams of EPA and DHA a day are needed; the usual 1000-milligram capsules often contain only 300 of that — which explains a large share of the missing effect. Plant ALA from linseed oil is converted at only a few per cent.

infoNumbers and timeframes

The omega-3 index counts as well supplied from eight per cent, low below four; in central Europe many people sit between four and six. It takes three to four months to respond to a new intake. Two portions of oily sea fish a week supply on average about 250 to 500 milligrams of EPA and DHA a day. Of plant ALA, only about five per cent is converted to EPA and under one per cent to DHA.

Possible complaints

associatedBalance rather than “deficiency”

The omega-6 to omega-3 ratio is often unfavourable — that’s the core.

associatedImportant for heart & brain

Omega-3s build cell membranes and act favourably.

associatedTrue deficiency rare

Clear deficiency diseases are rare — it’s about long-term prevention.

associatedMeasurable via the index

The omega-3 index gives a good picture of supply.

studiedSigns on the body

What a deficiency makes visible on the body — skin, nails, tongue, eyes and nerves. The signs are unspecific: they show where to look, they prove nothing.

Blood values

associatedOmega-3 index

Shows the share of EPA/DHA in red blood cells — a good mirror of supply.

Nutrients

associatedOmega-3 fatty acids

They lower the blood fats and act on the excitability of the heart muscle. Oily sea fish twice a week is the best-supported route; very high doses from capsules are not a harmless more.

studiedPotassium

Keeps the rhythm steady and lowers blood pressure. Water tablets drive it down, certain blood pressure drugs and a weak kidney drive it up — which is why it is checked under treatment.

associatedMagnesium

A lack favours extra beats and at the same time keeps a potassium deficiency going. Anyone replacing only the potassium sees no success while the magnesium is missing.

studiedSalt

Less salt lowers blood pressure measurably, and most of it is not in the salt cellar but in bread, cheese, cured meat and ready meals. With very low blood pressure the opposite applies.

Supplements

studiedOmega-3 (EPA/DHA)

250–500 mg EPA and DHA a day for maintenance, 1–2 g with raised blood fats. The packet often states the amount of fish oil, not the amount of EPA and DHA — the most common miscalculation when comparing.

studiedAlgae oil (vegan omega-3)

Supplies the same fatty acids as fish oil — the fish gets them from algae anyway. For anyone not eating fish this is the direct route rather than the detour via linseed oil.

infoMagnesium (glycinate/citrate)

Effective when deficient; effects on sleep and stress plausible but moderate. Too much causes loose stool.

Hormones

associatedInsulin

The fatty acids in the cell membrane help decide how flexible it is and how well the insulin receptor inside it works. The link is well described in the laboratory; in human studies the effects on sugar are small.

associatedEstradiol

From omega-6 come the messengers that contract the womb muscle — hence the link with period pain. Omega-3 shifts that balance over weeks, not days.

Food

studiedOily sea fish twice a week

Two portions of 100–150 g salmon, herring, mackerel or sardine give an average of 250–500 mg EPA and DHA a day — the amount the recommendations refer to.

studiedPlant omega-3 converts only partly

Linseed oil, walnuts and chia supply ALA. In humans only about 5–10 % becomes EPA and much less DHA — somewhat more in women. One tablespoon of linseed oil gives around 7 g ALA.

associatedThe ratio to omega-6

Both use the same enzymes. In today’s diet the ratio is often 15:1 in favour of omega-6; 5:1 or closer is considered better. That is reached more by adding omega-3 than by cutting back.

Alternative approaches — what people use

studiedOmega-3

Studied at 250–500 mg EPA and DHA a day for maintenance, 1–2 g with raised blood fats. Algae oil supplies the same fatty acids as fish oil — for anyone not eating fish.