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Tuberculosis

Tuberculosis

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Not extinct but treatable — the therapy takes long yet works reliably.

Also known as: tuberculosis · TB · consumption (old term)

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This compilation is for information and replaces neither medical diagnosis nor treatment. If you have symptoms, see a doctor.

A bacterial infection that most often affects the lung. It spreads through the air (fine droplets), but not every contact leads to illness: often the bacterium stays inactive in the body (latent tuberculosis) with no symptoms at all. When it becomes active, a persistent cough (often longer than three weeks, sometimes bloody), night sweats, fever, weight loss and malaise are typical. Important to know: tuberculosis is usually curable with a consistent, multi-month combination of antibiotics. The key is to complete the treatment fully.

Levers & pathways

studiedEarly assessment

If suspected: test, X-ray and sputum analysis — the earlier the better.

studiedComplete antibiotic therapy

The core point: a combination of several antibiotics over several months usually leads to a cure.

associatedDo not stop treatment early

Stopping too early favours resistant bacteria — so it must be seen through.

associatedProtect & screen close contacts

Close contacts should be examined; protective measures apply during the infectious phase.

infoWhat the medicine does — and what it does not

Four drugs at once for two months, then two for four months — six in all. The number is needed because otherwise the bacteria become resistant within weeks; the duration because part of the organisms lie dormant and are reached only slowly. A person is no longer infectious after about two to three weeks of treatment — so the symptoms improve long before the end. That very feeling is the reason for most discontinuations.

infoNumbers and timeframes

About a quarter of the world’s population carries the organism dormant; in five to ten in a hundred of them the illness breaks out during their life, considerably more often with weakened defences. From infection to a positive skin test, two to ten weeks pass. Treatment lasts six months; a person is no longer infectious after two to three weeks. The culture needs two to six weeks, because the organism divides only every twenty hours.

Possible complaints

associatedPersistent cough (>3 weeks)

Sometimes with bloody sputum — should be assessed.

associatedNight sweats & fever

Often a low fever over a longer period.

associatedWeight loss & malaise

Unintended weight loss and lasting tiredness.

associatedPossible as latent (no symptoms)

The bacterium can lie dormant for years and become active later.

Blood values

studiedESR (sedimentation rate)

Often clearly raised and staying raised over weeks. A normal value does not rule the illness out, though.

associatedCRP

Supplements the sedimentation rate. Neither says anything about the cause — they only show that an inflammation is running.

studiedBlood count

Often an anaemia and a shifted distribution of the white cells. The proof lies in the examination of the sputum and in the imaging.

associatedSodium

A low sodium occurs with long-drawn-out lung disease and belongs assessed too, because it explains tiredness and confusion.

Nutrients

studiedFluid

Fever, sweating and faster breathing clearly raise the need. Drinking enough keeps the mucus thin and the circulation steady — in children and older people it is the most important point of all.

associatedVitamin D

Low levels are common in chronic airway illnesses and go along with more infections. Correcting a deficiency is simple; for lung function itself it is no replacement for treatment.

associatedMagnesium

Relaxes the smooth muscle of the airways — which is why it is also given as an infusion in an emergency. For everyday use the tablet replaces no inhaler.

associatedZinc

Needed by the defence cells. For lozenges at the start of a cold there are hints of a slightly shortened duration; at a high dose over months zinc lowers copper.

studiedProtein

Antibodies and defence cells are protein. After several days with little appetite it is worth at least keeping the protein up — soup with egg, quark, yoghurt, lentils.

Supplements

infoVitamin D3 (+K2)

Clearly worthwhile and well studied when deficient; fewer data for the wider uses. Fat-soluble — check blood levels at high doses.

infoMagnesium (glycinate/citrate)

Effective when deficient; effects on sleep and stress plausible but moderate. Too much causes loose stool.

Hormones

studiedCortisol

A dormant tuberculosis can flare again under cortisone or under modern rheumatism medicines. This is why testing happens before such treatments — one of the most important preparatory steps of all.

studiedCalcitriol (vitamin D hormone)

As with sarcoidosis the inflammatory nodules themselves make the active form of vitamin D — which is why the calcium in the blood can rise. A vitamin D supplement is not a given here but a question put to the value.

associatedACTH

Historically tuberculosis was the most common reason for adrenal insufficiency — it destroys the adrenal glands from outside. In some parts of the world it still is today.

Food

studiedWeight and protein during treatment

Treatment lasts at least 6 months. Being underweight at the start is linked with a poorer course; weight gain in the first 2 months counts as a favourable sign.

studiedB6 with isoniazid

Isoniazid uses up vitamin B6 and can otherwise damage nerves. B6 is therefore usually given alongside — not an optional supplement but part of the treatment.

Alternative approaches — what people use

mixedVitamin D

Historically tuberculosis was treated with sun and mountain air — vitamin D lies behind that. As an addition to today’s treatment studies found small effects on healing time.

Frequencies — what is on file

traditionalTuberculosis

Listed values: 4 · 20 · 100 · 666 · 690 · 720 · 727 · 728 · 787 · 799 · 800 · 801 · 1500 · 1550 · 1600 Hz